The Dow Difference

NEW Video - Gordon Dow, Founder and Chief Technology Officer, on the Dow Difference

Watch it NOW

 

Reasons to work with Dow Pharmaceutical Sciences: Your Competitive Advantage.

Unmatched Experience with Topical Formulations

At Dow we focus only on topical products, so you know your product is in very experienced hands. After 30+ years, we know how to prevent or correct the unique problems that can occur during topical formulation development, scale-up and long term storage. Dow has successfully helped hundreds of companies develop stable, elegant, scalable formulations that are disease compatible and penetrate the skin as required. This is accomplished with a team of formulation, analytical and drug transport scientists using Dow’s unique formulation development process.

Novel In Vitro Skin Penetration Models

With Dow’s in vitro models using Bronaugh or Franz cells, you can screen multiple formulations for drug release and penetration into target tissue layers and through the skin. For dermatological products, freshly excised human skin from elective surgery is used for superior results. For ophthalmic products, newborn bovine eyes are used in vitro to test penetration through both ocular and scleral tissue in a unique model developed at Dow.

Unique Proof of Concept Clinical Models

bioskin®, Dow’s dermatology CRO subsidiary in Germany, offers unique proof-of-concept models for psoriasis and other indications. Time and variability are reduced by measuring the comparative efficacy of multiple test formulations against the industry standard within the same patient or within a small number of patients.

Intimate Knowledge of FDA Non-Clinical And Clinical Requirements

With so many client products in development, Dow interacts with the FDA Dermatology Division frequently. Between June 2005 and November 2006 Dow had four New Drug Applications (NDAs) approved, so we know how to get a topical product approved. We can write your regulatory development plans for non-clinical and clinical studies, and we can file your documents (IND, NDA, etc.) electronically using our Core Dossier software system.

Full Service One-Stop-Shop For Topical Product Development

At our facility in Petaluma, California, you can access all services required to support development of your topical product. These include formulation and in vitro drug penetration testing, analytical method development, stability testing, GMP manufacturing and labeling and distribution of clinical supplies to your test sites. We also can assist with the toxicology, clinical and regulatory components of your program through our Regulatory and Clinical Affairs Group. Coordinated by a Dow project manager, you have a full team of specialists in topical products working for you in one location. This should provide your best chance of success and fastest route to market, thus saving you time and money.